Natural killer cells complot with dendritic cells
نویسندگان
چکیده
منابع مشابه
Związki komórek NK z komórkami dendrytycznymi* Natural killer cells complot with dendritic cells
Komórki dendrytyczne (dendritic cells – DC) znane są głównie ze zdolności do prezentacji antygenów limfocytom T oraz udziału w polaryzacji odpowiedzi immunologicznej. Niedawne badania ujawniły jednak ich inne funkcje – immunoregulacyjne i cytotoksyczne. Z kolei komórki NK (natural killer cells – NK), uważane dotychczas za jednorodną populację limfocytów zdolnych do nieswoistego rozpoznawania i ...
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Circulating monocytes can differentiate into dendritic cells (moDCs), which are potent inducers of adaptive immune responses. Previous reports show that granulocyte macrophage-colony-stimulating factor (GM-CSF) and interleukin-4 induce monocyte differentiation into moDCs in vitro, but little is known about the physiological requirements that initiate moDC differentiation in vivo. Here we show t...
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We analyzed the interaction between human peripheral blood natural killer (NK) cells and monocyte-derived immature dendritic cells (DC). Fresh NK cells were activated, as indicated by the induced expression of the CD69 antigen, and their cytolytic activity was strongly augmented by contact with lipopolysaccharide (LPS)-treated mature DC, or with immature DC in the presence of the maturation sti...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2013
ISSN: 1732-2693
DOI: 10.5604/17322693.1040434